Research Profile: Drop, stop, and cycle: digital microfluidics meets digital PCR
نویسندگان
چکیده
منابع مشابه
Digital microfluidics.
Digital microfluidics (DMF) is an emerging liquid-handling technology that enables individual control over droplets on an open array of electrodes. These picoliter- to microliter-sized droplets, each serving as an isolated vessel for chemical processes, can be made to move, merge, split, and dispense from reservoirs. Because of its unique advantages, including simple instrumentation, flexible d...
متن کاملOpen-Surface Digital Microfluidics
Open-surface digital microfluidics refers to droplet manipulations in an open surface. Different chemical/biological reaction protocols can easily be demonstrated in the same device by reprogramming the order of droplet manipulations. While continuous-flow or liquid-plug microfluidics within microchannels have inherently limited programmability, there is no limit of reprogrammability in open-su...
متن کاملMachine vision for digital microfluidics.
Machine vision is widely used in an industrial environment today. It can perform various tasks, such as inspecting and controlling production processes, that may require humanlike intelligence. The importance of imaging technology for biological research or medical diagnosis is greater than ever. For example, fluorescent reporter imaging enables scientists to study the dynamics of gene networks...
متن کاملHydrogel discs for digital microfluidics.
Hydrogels are networks of hydrophilic polymer chains that are swollen with water, and they are useful for a wide range of applications because they provide stable niches for immobilizing proteins and cells. We report here the marriage of hydrogels with digital microfluidic devices. Until recently, digital microfluidics, a fluid handling technique in which discrete droplets are manipulated elect...
متن کاملDigital microfluidics using soft lithography.
Although microfluidic chips have demonstrated basic functionality for single applications, performing varied and complex experiments on a single device is still technically challenging. While many groups have implemented control software to drive the pumps, valves, and electrodes used to manipulate fluids in microfluidic devices, a new level of programmability is needed for end users to orchest...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2007
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac072000o